Publications

Lab members are highlighted in boldface.

  1. Hong J*, Hatchell KE*, Bradfield JP, Andrew B, Alessandra C, Chao-Qiang L, Langefeld CD, Lu L, Lu Y, Lutsey PL, Musani SK, Nalls MA, Robinson-Cohen C, Roizen JD, Saxena R, Tucker KL, Ziegler JT, Arking DE, Bis JC, Boerwinkle E, Bottinger EP, Bowden DW, Gilsanz V, Houston DK, Kalkwarf HJ, Kelly A, Lappe JM, Liu Y, Michos ED, Oberfield SE, Palmer ND, Rotter JI, Sapkota B, Shepherd JA, Wilson JG, Basu S, de Boer IH, Divers J, Freedman BI, Grant SFA, Hakanarson H, Harris TB, Kestenbaum BR, Kritchevsky SB, Loos RJF, Norris JM, Norwood AF, Ordovas JM, Pankow JS, Psaty BM, Sanhgera DK, Wagenknecht LE, Zemel BS, Meigs J, Dupuis J, Florez JC, Wang T, Liu CT**, Engelman CD**, Billings LK**. Trans-ethnic evaluation identifies novel low frequency loci associated with 25-hydroxyvitamin D concentrations. J Clin Endocrinol Metab 2018 Jan 9. doi: 10.1210/jc.2017-01802. (Epub ahead of print).*Joint first authors; **Joint senior authors (consortium paper)
  2. Engelman CD, Darst BF, Bilgel M, Vasiljevic E, Koscik RL, Jedynak BM, Johnson SC. The effect of rare variants in TREM2 and PLD3 on longitudinal cognitive function in the Wisconsin Registry for Alzheimer’s Prevention. Neurobiology of Aging 2017 Dec 29. doi: 10.1016/j.neurobiolaging.2017.12.025. (Epub ahead of print; http://authors.elsevier.com/sd/article/S0197458017304220). NIHMS ID: NIHMS939446.
  3. Darst BF, Malecki KC, Engelman CD. Using recursive feature elimination in random forest to account for correlated variables in high dimensional data. BMC Genetics 2018, 19(Suppl 1):65.
  4. Zuelsdorff ML, Koscik RL, Okonkwo OC, Peppard PE, Hermann BP, Sager MA, Johnson SC, Engelman CD. Social support and verbal interaction are differentially associated with cognitive function in midlife and older age. Aging, Neuropsychology and Cognition 2017 Dec 15:1-17 (Epub ahead of print; doi: 10.1080/13825585.2017.1414769).
  5. Zuelsdorff ML, Koscik RL, Okonkwo OC, Peppard PE, Hermann BP, Sager MA, Johnson SC, Engelman CD. Reliability of a novel social activity questionnaire.  Journal of Aging and Health 2018 Feb;30(2):305-320.  PMCID: PMC5449232.
  6. Darst BF, Koscik RL, Racine AM, Oh JM, Krause RA, Carlsson CM, Zetterberg H, Blennow K, Christian BT, Bendlin BB, Okonkwo OC, Hogan KJ, Hermann BP, Sager MA, Asthana S, Johnson SC, Engelman CD.  Pathway-specific polygenic risk scores as predictors of amyloid-b deposition and cognitive function in a sample at increased risk for Alzheimer’s disease. J Alzheimers Dis 2017;55(2):473-484.  PMCID: PMC5123972.
  7. Sippy R, Kolesar JM, Darst BF, Engelman CD.  Prioritization of family member sequencing for the detection of rare variants.  BMC Proceedings 2016 Oct 18;10(Suppl 7):227-231.  PMCID: PMC5133500.
  8. Darst BF, Engelman CD.  Transmission and decorrelation methods for detecting rare variants using sequencing data from related individuals.  BMC Proceedings 2016 Oct 18;10(Suppl 7):203-207.  PMCID: PMC5133523.
  9. Engelman CD, Greenwood CMT, Bailey JN, Cantor RM, Kent JW, Konig IR, Bermejo JL, Melton PE, Santorico SA, Schillert A, Wijsman EM, MacCluer JW, Almasy L.  Genetic Analysis Workshop 19: methods and strategies for analyzing human sequence and gene expression data in extended families and unrelated individuals.  BMC Proceedings 2016 Oct 18;10(Suppl 7):67-70.  PMCID: PMC5133501.
  10. Darst BF, Koscik RL, Hermann BP, La Rue A, Sager MA, Johnson SC, Engelman CD.  Heritability of Cognitive Traits Among Siblings with a Parental History of Alzheimer’s Disease.  J Alzheimers Dis 2015 Jan; 45(4): 1149-55. PMCID: PMC4398625.
  11. Sung YJ, Korthauer KD, Swartz MD, Engelman CD.  Methods for collapsing multiple rare variants in whole genome sequence data.  Genet Epidemiol 2014 Aug; 38(S1): S13-20. PMCID: PMC4558905.
  12. Yao C, Leng N, Weigel KA, Lee KE, Engelman CD, Meyers KJ.  Prediction of genetic contributions to complex traits using whole genome sequencing data.  BMC Proceedings 2014 Jun; 8(Suppl 1): S68. PMCID: PMC4143683.
  13. Engelman CD, Bo R, Zuelsdorff M, Steltenpohl H, Kirby T, Nieto FJ.  Epidemiologic study of the C-3 epimer of 25-hydroxyvitamin D3 in a population-based sample.  Clin Nutr 2014 Jun; 33(3): 421-5. PMCID: PMC3884039.
  14. Engelman CD, Koscik RL, Jonaitis EM, Hermann BP, La Rue A, Sager MA.  Investigation of TREM2 variant in the Wisconsin Registry for Alzheimer’s Prevention.  Neurobiology of Aging 2014 Jun; 35(6): 1252-4.  PMCID: PMC3961539.
  15. Engelman CD.  Towards personalized prevention of obesity: Can vitamin D negate the FTO effect?  Diabetes 2014 Feb; 63(2): 405-6. (Invited editorial).
  16. Zuelsdorff ML, Engelman CD, Friedman EM, Koscik RL, Jonaitis EM, La Rue A, Sager MA.  Stressful Events, Social Support, and Cognitive Function in Middle-aged Adults with a Family History of Alzheimer’s Disease.  J Aging Health 2013 Sep; 25(6): 944-59.  PMCID: PMC3769466.
  17. Engelman CD, Koscik RL, Jonaitis EM, Okonkwo OC, Hermann BP, La Rue A, Sager MA.  Interaction between two cholesterol metabolism genes influences memory: Findings from the Wisconsin Registry for Alzheimer’s Prevention.  J Alzheimers Dis 2013 Aug; 36(4): 749-57. PMCID: PMC3759032.
  18. Engelman CD, Meyers KJ, Iyengar SK, Liu Z, Karki CK, Igo, Jr RP, Truitt B, Robinson J, Sarto GE, Wallace R, Blodi BA, Klein ML, Tinker L, LeBlanc ES, Jackson RD, Song Y, Manson JE, Mares JA, Millen AE.  Vitamin D intake and season modify the effects of the GC and CYP2R1 genes on 25-hydroxyvitamin D concentrations. J Nutr 2013 Jan; 143(1): 17-26.  PMCID: PMC3521459
  19. Bueno Filho JS, Morota G, Tran QT, Maenner MJ, Vera-Cala LM, Engelman CD, Meyers KJ.  Analysis of human mini-exome sequencing data using a Bayesian hierarchical mixture model: Genetic Analysis Workshop 17.  BMC Proceedings 2011 Nov; 5(S9): S93: 1-8. PMCID: PMC3287935
  20. Ye KQ and Engelman CD.  Detecting Multiple Causal Rare Variants in Exome Sequence Data. Genet Epidemiol 2011 Nov; 35(S1): 18-21. PMCID: PMC3271433
  21. Engelman CD.  Vitamin D recommendations: the saga continues.  J Clin Endocrinol Metab 2011 Oct; 96(10): 3065-6. (Invited editorial)
  22. Engelman CD, Meyers KJ, Ziegler JT, Taylor KD, Palmer ND, Haffner SM, Fingerlin TE, Wagenknecht LE, Rotter JI, Bowden DW, Langefeld CD, Norris JM.  Genome-wide association study of vitamin D concentrations in Hispanic Americans: The IRAS Family Study.  J Steroid Biochem Mol Biol 2010 Oct; 122(4): 186-92. PMCID: PMC2949505
  23. Yao L, Zhong W, Zhang Z, Maenner MJ, Engelman CD.  Classification tree for selection of single-nucleotide polymorphism (SNP)-by-SNP interactions related to heart disease: Framingham Heart Study.  BMC Proceedings 2009 Dec; 3(S7): S83: 1-6.  PMCID: PMC2795986
  24. Engelman CD, Baurley JW, Chiu YF, Joubert BR, Maenner MJ, Murcray CE, Shi G, Gauderman, WJ.  Detecting Gene-Environment Interactions in Genome-Wide Association Data.  Genet Epidemiol 2009 Nov; 33(S1): S68-73.  PMCID: PMC2924567
  25. Schmitz KJ, Skinner HG, Bautista LE, Fingerlin TE, Langefeld CD, Hicks PJ, Haffner SM, Bryer-Ash M, Wagenknecht LE, Bowden DW, Norris JM, Engelman CD.  Association of 25-hydroxyvitamin D with Blood Pressure in Predominantly 25-hydroxyvitamin D Deficient Hispanic and African Americans.  Am J Hypertens 2009 Aug; 22(8): 367-70.  PMCID: PMC2865679
  26. Engelman CD, Fingerlin TE, Langefeld CD, Hicks PJ, Rich SS, Wagenknecht LE, Bowden DW, Norris JM.  Genetic and environmental determinants of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels in Hispanic and African Americans.  J Clin Endocrinol Metab 2008 Sep; 93(9): 3381-8.  PMCID: PMC2567851